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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
|
|---|---|
| Published in |
Genome Biology, December 2015
|
| DOI | 10.1186/s13059-015-0843-6 |
| Pubmed ID | |
| Authors |
Wei Li, Johannes Köster, Han Xu, Chen-Hao Chen, Tengfei Xiao, Jun S. Liu, Myles Brown, X. Shirley Liu |
| Abstract |
High-throughput CRISPR screens have shown great promise in functional genomics. We present MAGeCK-VISPR, a comprehensive quality control (QC), analysis, and visualization workflow for CRISPR screens. MAGeCK-VISPR defines a set of QC measures to assess the quality of an experiment, and includes a maximum-likelihood algorithm to call essential genes simultaneously under multiple conditions. The algorithm uses a generalized linear model to deconvolute different effects, and employs expectation-maximization to iteratively estimate sgRNA knockout efficiency and gene essentiality. MAGeCK-VISPR also includes VISPR, a framework for the interactive visualization and exploration of QC and analysis results. MAGeCK-VISPR is freely available at http://bitbucket.org/liulab/mageck-vispr . |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 20% |
| India | 1 | 10% |
| United Kingdom | 1 | 10% |
| Unknown | 6 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Scientists | 3 | 30% |
| Science communicators (journalists, bloggers, editors) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 491 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| China | 2 | <1% |
| Switzerland | 1 | <1% |
| Germany | 1 | <1% |
| Canada | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 485 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 129 | 26% |
| Researcher | 108 | 22% |
| Student > Master | 52 | 11% |
| Student > Bachelor | 35 | 7% |
| Student > Doctoral Student | 23 | 5% |
| Other | 48 | 10% |
| Unknown | 96 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 184 | 37% |
| Agricultural and Biological Sciences | 100 | 20% |
| Medicine and Dentistry | 25 | 5% |
| Immunology and Microbiology | 16 | 3% |
| Computer Science | 15 | 3% |
| Other | 51 | 10% |
| Unknown | 100 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2024.
All research outputs
#1,299,323
of 25,373,627 outputs
Outputs from Genome Biology
#1,005
of 4,467 outputs
Outputs of similar age
#21,756
of 395,908 outputs
Outputs of similar age from Genome Biology
#30
of 78 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 395,908 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.