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Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation

Overview of attention for article published in BMC Immunology, December 2015
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  • Good Attention Score compared to outputs of the same age and source (75th percentile)

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Title
Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation
Published in
BMC Immunology, December 2015
DOI 10.1186/s12865-015-0135-7
Pubmed ID
Authors

Elizabeth O. Stenger, Lakshmanan Krishnamurti, Jacques Galipeau

Abstract

Mesenchymal stromal cells (MSCs) are multipotent progenitor cells known to modulate the immune system and to promote hematopoiesis. These dual effects make MSCs attractive for use as cellular therapy in hematopoietic cell transplantation (HCT). MSCs can be used peri-HCT or pre-engraftment to modulate immune reconstitution, promoting hematopoietic stem cell (HSC) engraftment and/or preventing graft-versus-host disease (GVHD). Pre-clinical studies have demonstrated that MSCs can potentiate HSC engraftment and prevent GVHD in a variety of animal models. Clinical trials have been small and largely non-randomized but have established safety and early evidence of efficacy, supporting the need for larger randomized trials.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
United States 1 3%
Unknown 30 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 28%
Researcher 6 19%
Student > Bachelor 4 13%
Student > Postgraduate 3 9%
Other 2 6%
Other 6 19%
Unknown 2 6%
Readers by discipline Count As %
Medicine and Dentistry 8 25%
Biochemistry, Genetics and Molecular Biology 6 19%
Agricultural and Biological Sciences 6 19%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Immunology and Microbiology 2 6%
Other 7 22%
Unknown 1 3%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2016.
All research outputs
#14,718,998
of 23,577,654 outputs
Outputs from BMC Immunology
#274
of 592 outputs
Outputs of similar age
#208,201
of 393,751 outputs
Outputs of similar age from BMC Immunology
#1
of 8 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 592 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 393,751 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them