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Mendeley readers
Attention Score in Context
| Title |
Cardiovascular magnetic resonance evidence of myocardial fibrosis and its clinical significance in adolescent and adult patients with Ebstein's anomaly
|
|---|---|
| Published in |
Critical Reviews in Diagnostic Imaging, September 2018
|
| DOI | 10.1186/s12968-018-0488-1 |
| Pubmed ID | |
| Authors |
Dan Yang, Xiao Li, Jia-Yu Sun, Wei Cheng, Andreas Greiser, Tian-Jing Zhang, Hong Liu, Ke Wan, Yong Luo, Qi An, Yiu-Cho Chung, Yuchi Han, Yu-Cheng Chen |
| Abstract |
Myocardial fibrosis is a common pathophysiological process that is related to ventricular remodeling in congenital heart disease. However, the presence, characteristics, and clinical significance of myocardial fibrosis in Ebstein's anomaly have not been fully investigated. This study aimed to evaluate myocardial fibrosis using cardiovascular magnetic resonance (CMR) late gadolinium enhancement (LGE) and T1 mapping techniques, and to explore the significance of myocardial fibrosis in adolescent and adult patients with Ebstein's anomaly. Forty-four consecutive patients with unrepaired Ebstein's anomaly (34.0 ± 16.2 years; 18 males), and an equal number of age- and gender-matched controls, were included. A comprehensive CMR protocol consisted of cine, LGE, and T1 mapping by modified Look-Locker inversion recovery (MOLLI) sequences were performed. Ventricular functional parameters, native T1, extracellular volume (ECV), and LGE were analyzed. Associations between myocardial fibrosis and disease severity, ventricular function, and NYHA classification were analyzed. LGE was found in 10 (22.7%) patients. Typical LGE in Ebstein's anomaly was located in the endocardium of the septum within the right ventricle (RV). The LV ECV of Ebstein's anomaly were significantly higher than those of the controls (30.0 ± 3.8% vs. 25.3 ± 2.3%, P < 0.001). An increased ECV was found to be independent of the existence of LGE. Positive LGE or higher ECV (≥30%) was associated with larger fRV volume, aRV volume, increased disease severity, and worse NYHA functional class. In addition, ECV was significantly correlated with the LV ejection fraction (P < 0.001). Both focal and diffuse myocardial fibrosis were observed in adolescent and adult patients with Ebstein's anomaly. Increased diffuse fibrosis is associated with worse LV function, increased Ebstein's severity, and worse clinical status. |
X Demographics
The data shown below were collected from the profiles of 34 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 18% |
| United States | 5 | 15% |
| Spain | 4 | 12% |
| Saudi Arabia | 2 | 6% |
| Argentina | 2 | 6% |
| Peru | 1 | 3% |
| Russia | 1 | 3% |
| Turkey | 1 | 3% |
| India | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 8 | 24% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 65% |
| Scientists | 6 | 18% |
| Practitioners (doctors, other healthcare professionals) | 5 | 15% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 8 | 15% |
| Student > Postgraduate | 7 | 13% |
| Student > Master | 5 | 10% |
| Researcher | 5 | 10% |
| Student > Doctoral Student | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 16 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 48% |
| Engineering | 4 | 8% |
| Psychology | 1 | 2% |
| Biochemistry, Genetics and Molecular Biology | 1 | 2% |
| Materials Science | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 19 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2019.
All research outputs
#1,926,822
of 25,711,518 outputs
Outputs from Critical Reviews in Diagnostic Imaging
#64
of 1,386 outputs
Outputs of similar age
#39,425
of 352,737 outputs
Outputs of similar age from Critical Reviews in Diagnostic Imaging
#5
of 16 outputs
Altmetric has tracked 25,711,518 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,386 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,737 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.