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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Bispecific antibodies and their applications
|
|---|---|
| Published in |
Journal of Hematology & Oncology, December 2015
|
| DOI | 10.1186/s13045-015-0227-0 |
| Pubmed ID | |
| Authors |
Gaowei Fan, Zujian Wang, Mingju Hao, Jinming Li |
| Abstract |
Bispecific antibodies (BsAbs) recognize two different epitopes. This dual specificity opens up a wide range of applications, including redirecting T cells to tumor cells, blocking two different signaling pathways simultaneously, dual targeting of different disease mediators, and delivering payloads to targeted sites. The approval of catumaxomab (anti-EpCAM and anti-CD3) and blinatumomab (anti-CD19 and anti-CD3) has become a major milestone in the development of bsAbs. Currently, more than 60 different bsAb formats exist, some of them making their way into the clinical pipeline. This review summarizes diverse formats of bsAbs and their clinical applications and sheds light on strategies to optimize the design of bsAbs. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 29% |
| Denmark | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 449 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | <1% |
| France | 1 | <1% |
| India | 1 | <1% |
| Belgium | 1 | <1% |
| Denmark | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 443 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 82 | 18% |
| Student > Master | 68 | 15% |
| Student > Ph. D. Student | 67 | 15% |
| Researcher | 58 | 13% |
| Other | 27 | 6% |
| Other | 37 | 8% |
| Unknown | 110 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 111 | 25% |
| Agricultural and Biological Sciences | 63 | 14% |
| Medicine and Dentistry | 48 | 11% |
| Immunology and Microbiology | 34 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 28 | 6% |
| Other | 48 | 11% |
| Unknown | 117 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2024.
All research outputs
#1,115,970
of 25,734,859 outputs
Outputs from Journal of Hematology & Oncology
#54
of 1,301 outputs
Outputs of similar age
#18,640
of 398,047 outputs
Outputs of similar age from Journal of Hematology & Oncology
#1
of 12 outputs
Altmetric has tracked 25,734,859 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,301 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.3. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 398,047 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.