Title |
Non-coding yet non-trivial: a review on the computational genomics of lincRNAs
|
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Published in |
BioData Mining, December 2015
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DOI | 10.1186/s13040-015-0075-z |
Pubmed ID | |
Authors |
Travers Ching, Jayson Masaki, Jason Weirather, Lana X. Garmire |
Abstract |
Long intergenic non-coding RNAs (lincRNAs) represent one of the most mysterious RNA species encoded by the human genome. Thanks to next generation sequencing (NGS) technology and its applications, we have recently witnessed a surge in non-coding RNA research, including lincRNA research. Here, we summarize the recent advancement in genomics studies of lincRNAs. We review the emerging characteristics of lincRNAs, the experimental and computational approaches to identify lincRNAs, their known mechanisms of regulation, the computational methods and resources for lincRNA functional predictions, and discuss the challenges to understanding lincRNA comprehensively. |
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Unknown | 3 | 50% |
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Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 22% |
Student > Bachelor | 8 | 12% |
Student > Master | 7 | 10% |
Student > Doctoral Student | 4 | 6% |
Other | 9 | 13% |
Unknown | 9 | 13% |
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Business, Management and Accounting | 2 | 3% |
Other | 6 | 9% |
Unknown | 10 | 15% |