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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Protective effect of probiotics on Salmonella infectivity assessed with combined in vitro gut fermentation-cellular models
|
|---|---|
| Published in |
BMC Microbiology, December 2011
|
| DOI | 10.1186/1471-2180-11-264 |
| Pubmed ID | |
| Authors |
Annina Zihler, Mélanie Gagnon, Christophe Chassard, Christophe Lacroix |
| Abstract |
Accurate assessment of probiotics with targeted anti-Salmonella activity requires suitable models accounting for both, microbe-microbe and host-microbe interactions in gut environments. Here we report the combination of two original in vitro intestinal models closely mimicking the complex in vivo conditions of the large intestine. Effluents from continuous in vitro three-stage fermentation colonic models of Salmonella Typhimurium infection inoculated with immobilized child microbiota and Salmonella were directly applied to confluent mucus-secreting HT29-MTX cell layers. The effects of Salmonella, addition of two bacteriocinogenic strains, Bifidobacterium thermophilum RBL67 (thermophilicin B67) and Escherichia coli L1000 (microcin B17), and inulin were tested on Salmonella growth and interactions with epithelial cell layers. Salmonella adhesion and invasion were investigated and epithelial integrity assessed by transepithelial electrical resistance (TER) measurements and confocal microscopy observation. Data from complex effluents were compared with pure Salmonella cultures. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 50% |
| India | 1 | 25% |
| United States | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Italy | 1 | <1% |
| Argentina | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 103 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 19% |
| Student > Ph. D. Student | 19 | 18% |
| Student > Doctoral Student | 12 | 11% |
| Student > Master | 10 | 9% |
| Student > Bachelor | 9 | 8% |
| Other | 19 | 18% |
| Unknown | 18 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 38% |
| Biochemistry, Genetics and Molecular Biology | 14 | 13% |
| Medicine and Dentistry | 12 | 11% |
| Immunology and Microbiology | 10 | 9% |
| Nursing and Health Professions | 3 | 3% |
| Other | 8 | 7% |
| Unknown | 19 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2011.
All research outputs
#15,272,728
of 25,654,806 outputs
Outputs from BMC Microbiology
#1,373
of 3,513 outputs
Outputs of similar age
#158,523
of 250,241 outputs
Outputs of similar age from BMC Microbiology
#15
of 31 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,513 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,241 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.