Title |
Definition of the viral targets of protective HIV-1-specific T cell responses
|
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Published in |
Journal of Translational Medicine, December 2011
|
DOI | 10.1186/1479-5876-9-208 |
Pubmed ID | |
Authors |
Beatriz Mothe, Anuska Llano, Javier Ibarrondo, Marcus Daniels, Cristina Miranda, Jennifer Zamarreño, Vanessa Bach, Rosario Zuniga, Susana Pérez-Álvarez, Christoph T Berger, Maria C Puertas, Javier Martinez-Picado, Morgane Rolland, Marilu Farfan, James J Szinger, William H Hildebrand, Otto O Yang, Victor Sanchez-Merino, Chanson J Brumme, Zabrina L Brumme, David Heckerman, Todd M Allen, James I Mullins, Guadalupe Gómez, Philip J Goulder, Bruce D Walker, Jose M Gatell, Bonaventura Clotet, Bette T Korber, Jorge Sanchez, Christian Brander |
Abstract |
The efficacy of the CTL component of a future HIV-1 vaccine will depend on the induction of responses with the most potent antiviral activity and broad HLA class I restriction. However, current HIV vaccine designs are largely based on viral sequence alignments only, not incorporating experimental data on T cell function and specificity. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 1% |
South Africa | 1 | <1% |
Germany | 1 | <1% |
United Kingdom | 1 | <1% |
Japan | 1 | <1% |
Unknown | 133 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 36 | 26% |
Student > Ph. D. Student | 20 | 14% |
Student > Bachelor | 11 | 8% |
Student > Doctoral Student | 9 | 6% |
Student > Master | 9 | 6% |
Other | 26 | 19% |
Unknown | 28 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 34 | 24% |
Medicine and Dentistry | 28 | 20% |
Immunology and Microbiology | 23 | 17% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Mathematics | 4 | 3% |
Other | 8 | 6% |
Unknown | 36 | 26% |