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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Targeting the indoleamine 2,3-dioxygenase pathway in cancer
|
|---|---|
| Published in |
Journal for Immunotherapy of Cancer, December 2015
|
| DOI | 10.1186/s40425-015-0094-9 |
| Pubmed ID | |
| Authors |
Yong Wha Moon, Joud Hajjar, Patrick Hwu, Aung Naing |
| Abstract |
Tumor cells escape the immune surveillance system of the host through a process called immune tolerance. Immunotherapy targets molecules that serve as checks and balances in the regulation of immune response. Indoleamine-2,3-dioxygenase (IDO) is an intracellular enzyme, which through the process of tryptophan depletion exerts an immunosuppressive effect, facilitating immune escape of tumors. This review summarizes our current knowledge on IDO expression in malignancies, the IDO inhibitors that are currently available and those under clinical development. |
X Demographics
The data shown below were collected from the profiles of 29 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 11 | 38% |
| Spain | 2 | 7% |
| Italy | 1 | 3% |
| Turkey | 1 | 3% |
| Unknown | 14 | 48% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 52% |
| Practitioners (doctors, other healthcare professionals) | 7 | 24% |
| Scientists | 6 | 21% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 309 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 2 | <1% |
| Italy | 1 | <1% |
| France | 1 | <1% |
| Unknown | 305 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 17% |
| Researcher | 48 | 16% |
| Student > Master | 38 | 12% |
| Student > Bachelor | 34 | 11% |
| Other | 21 | 7% |
| Other | 54 | 17% |
| Unknown | 63 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 61 | 20% |
| Medicine and Dentistry | 56 | 18% |
| Agricultural and Biological Sciences | 36 | 12% |
| Immunology and Microbiology | 33 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 18 | 6% |
| Other | 34 | 11% |
| Unknown | 71 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 January 2024.
All research outputs
#1,257,574
of 25,663,438 outputs
Outputs from Journal for Immunotherapy of Cancer
#300
of 3,481 outputs
Outputs of similar age
#20,834
of 397,805 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#1
of 96 outputs
Altmetric has tracked 25,663,438 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,481 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 397,805 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.