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Sub-cellular internalization and organ specific oral delivery of PABA nanoparticles by side chain variation

Overview of attention for article published in Journal of Nanobiotechnology, March 2011
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Title
Sub-cellular internalization and organ specific oral delivery of PABA nanoparticles by side chain variation
Published in
Journal of Nanobiotechnology, March 2011
DOI 10.1186/1477-3155-9-10
Pubmed ID
Authors

Jhillu S Yadav, Pragna P Das, T Lakshminarayan Reddy, Indira Bag, Priyadarshini M Lavanya, Bulusu Jagannadh, Debendra K Mohapatra, Manika Pal Bhadra, Utpal Bhadra

Abstract

Organic nanomaterials having specific biological properties play important roles in in vivo delivery and clearance from the live cells. To develop orally deliverable nanomaterials for different biological applications, we have synthesized several fluorescently labelled, self-assembled PABA nanoparticles using possible acid side chain combinations and tested against insect and human cell lines and in vivo animal model. Flurophores attached to nanostructures help in rapid in vivo screening and tracking through complex tissues. The sub-cellular internalization mechanism of the conjugates was determined. A set of physio-chemical parameters of engineered nanoskeletons were also defined that is critical for preferred uptake in multiple organs of live Drosophila.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 38%
Student > Postgraduate 2 15%
Researcher 2 15%
Professor 1 8%
Student > Master 1 8%
Other 0 0%
Unknown 2 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 31%
Pharmacology, Toxicology and Pharmaceutical Science 2 15%
Biochemistry, Genetics and Molecular Biology 1 8%
Computer Science 1 8%
Medicine and Dentistry 1 8%
Other 1 8%
Unknown 3 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2011.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Journal of Nanobiotechnology
#976
of 1,915 outputs
Outputs of similar age
#105,012
of 120,365 outputs
Outputs of similar age from Journal of Nanobiotechnology
#6
of 6 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,915 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,365 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.