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X Demographics
Mendeley readers
Attention Score in Context
| Title |
HDACi and Nrf2: not from alpha to omega but from acetylation to OA
|
|---|---|
| Published in |
Arthritis Research & Therapy, December 2015
|
| DOI | 10.1186/s13075-015-0885-x |
| Pubmed ID | |
| Authors |
Holger Jahr |
| Abstract |
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is probably the most important ubiquitously expressed little protein that you have never heard of. Discovered more than 20 years ago, it is now known as a master regulator of redox homeostasis, controlling a plethora of cytoprotective phase II anti-oxidant enzymes. Regulation of gene expression by histone acetyltransferases and histone deacetylases drives the etiology of many age-related human diseases, including osteoarthritis. In Arthritis Research & Therapy, Cai et al. explore systemic histone deacetylase inhibition as a strategy to prevent osteoarthritis and identify a role for Nrf2 in preventing cartilage degeneration. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 11 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 18% |
| Student > Doctoral Student | 2 | 18% |
| Student > Bachelor | 1 | 9% |
| Student > Master | 1 | 9% |
| Unknown | 5 | 45% |
| Readers by discipline | Count | As % |
|---|---|---|
| Environmental Science | 1 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 9% |
| Biochemistry, Genetics and Molecular Biology | 1 | 9% |
| Nursing and Health Professions | 1 | 9% |
| Agricultural and Biological Sciences | 1 | 9% |
| Other | 2 | 18% |
| Unknown | 4 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 January 2016.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#2,907
of 3,381 outputs
Outputs of similar age
#290,686
of 394,029 outputs
Outputs of similar age from Arthritis Research & Therapy
#112
of 113 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,029 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 113 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.