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The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer

Overview of attention for article published in Journal for Immunotherapy of Cancer, December 2015
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Title
The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer
Published in
Journal for Immunotherapy of Cancer, December 2015
DOI 10.1186/s40425-015-0102-0
Pubmed ID
Authors

Thaïs Baert, Tina Verschuere, Anaïs Van Hoylandt, Rik Gijsbers, Ignace Vergote, An Coosemans

Abstract

Reliable mouse models are key in the discovery and development of novel anticancer treatments. Non-invasive monitoring techniques such as bioluminescence imaging (BLI) are useful tools to determine tumor engraftment and evaluate tumor growth. However, the development of ascites in ovarian cancer mouse models leads to possible difficulties. Ascites can interfere with the set-up of correct end points and can interfere with the evaluation of tumor volume using BLI. We provide optimized euthanasia criteria and in vivo data underlining the pitfalls of BLI.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 82 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 18%
Student > Bachelor 13 16%
Researcher 11 13%
Student > Master 9 11%
Student > Doctoral Student 5 6%
Other 8 10%
Unknown 21 26%
Readers by discipline Count As %
Medicine and Dentistry 16 20%
Biochemistry, Genetics and Molecular Biology 15 18%
Immunology and Microbiology 10 12%
Agricultural and Biological Sciences 7 9%
Unspecified 2 2%
Other 5 6%
Unknown 27 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2020.
All research outputs
#16,048,009
of 25,374,917 outputs
Outputs from Journal for Immunotherapy of Cancer
#2,683
of 3,421 outputs
Outputs of similar age
#216,402
of 396,230 outputs
Outputs of similar age from Journal for Immunotherapy of Cancer
#74
of 97 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,421 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.4. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 396,230 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.