Title |
Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer
|
---|---|
Published in |
World Journal of Surgical Oncology, January 2016
|
DOI | 10.1186/s12957-015-0755-7 |
Pubmed ID | |
Authors |
Rebecca Zhu, Gabriella Grisotti, Ronald R. Salem, Sajid A. Khan |
Abstract |
Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, accounts for 3 % of newly diagnosed cases of colorectal cancer. While a partial or subtotal colectomy is indicated for early stage disease, there is a paucity of data addressing locally advanced disease involving the foregut. We report two patients with hereditary nonpolyposis colorectal cancer presenting with locally advanced colon cancer surgically managed by pancreaticoduodenectomy with en bloc partial colectomy and a review of the literature. Locally advanced colorectal cancer in HNPCC is a rare clinical entity that requires special surgical consideration. Multidisciplinary treatment, including multi-visceral resection, offers the best long-term outcome. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 19% |
Student > Bachelor | 5 | 16% |
Researcher | 4 | 13% |
Student > Postgraduate | 3 | 10% |
Student > Master | 3 | 10% |
Other | 6 | 19% |
Unknown | 4 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 45% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Agricultural and Biological Sciences | 3 | 10% |
Social Sciences | 3 | 10% |
Computer Science | 1 | 3% |
Other | 1 | 3% |
Unknown | 6 | 19% |