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Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer

Overview of attention for article published in World Journal of Surgical Oncology, January 2016
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Title
Pancreaticoduodenectomy for locally advanced colon cancer in hereditary nonpolyposis colorectal cancer
Published in
World Journal of Surgical Oncology, January 2016
DOI 10.1186/s12957-015-0755-7
Pubmed ID
Authors

Rebecca Zhu, Gabriella Grisotti, Ronald R. Salem, Sajid A. Khan

Abstract

Hereditary nonpolyposis colorectal cancer (HNPCC), or Lynch syndrome, accounts for 3 % of newly diagnosed cases of colorectal cancer. While a partial or subtotal colectomy is indicated for early stage disease, there is a paucity of data addressing locally advanced disease involving the foregut. We report two patients with hereditary nonpolyposis colorectal cancer presenting with locally advanced colon cancer surgically managed by pancreaticoduodenectomy with en bloc partial colectomy and a review of the literature. Locally advanced colorectal cancer in HNPCC is a rare clinical entity that requires special surgical consideration. Multidisciplinary treatment, including multi-visceral resection, offers the best long-term outcome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Student > Bachelor 5 16%
Researcher 4 13%
Student > Postgraduate 3 10%
Student > Master 3 10%
Other 6 19%
Unknown 4 13%
Readers by discipline Count As %
Medicine and Dentistry 14 45%
Biochemistry, Genetics and Molecular Biology 3 10%
Agricultural and Biological Sciences 3 10%
Social Sciences 3 10%
Computer Science 1 3%
Other 1 3%
Unknown 6 19%