... an abnormally low ratio of patient numbers to study site, spin and/or omissions of clinically relevant findings in the abstracts, and conclusions that focused on secondary endpoints and surrogate markers. These characteristics are from Barbour et al.
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...4/ We suggest that the trial could be a "seeding trial", a trial driven by marketing interest. Seeding trials enroll typically a low number of patients from a large number of sites. See this paper... https://t.co/KixFIQeaFW
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Seeding trials are « industry-funded drug trials that are done more for marketing purposes than science». https://t.co/KixFIQeaFW
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Analysis of trial documentation has revealed that some industry-funded trials may be done more for marketing purposes than scientific endeavour. Seeding Trials? @carlheneghan @fgodlee @bengoldacre @Opsore @RichardLehman1 @MeshCampaign @BioMedCentral http