Title |
Radiotherapy and "new" drugs-new side effects?
|
---|---|
Published in |
Radiation Oncology, December 2011
|
DOI | 10.1186/1748-717x-6-177 |
Pubmed ID | |
Authors |
Maximilian Niyazi, Cornelius Maihoefer, Mechthild Krause, Claus Rödel, Wilfried Budach, Claus Belka |
Abstract |
Targeted drugs have augmented the cancer treatment armamentarium. Based on the molecular specificity, it was initially believed that these drugs had significantly less side effects. However, currently it is accepted that all of these agents have their specific side effects. Based on the given multimodal approach, special emphasis has to be placed on putative interactions of conventional cytostatic drugs, targeted agents and other modalities. The interaction of targeted drugs with radiation harbours special risks, since the awareness for interactions and even synergistic toxicities is lacking. At present, only limited is data available regarding combinations of targeted drugs and radiotherapy. This review gives an overview on the current knowledge on such combined treatments. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Portugal | 1 | <1% |
Germany | 1 | <1% |
Italy | 1 | <1% |
Unknown | 118 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 24 | 20% |
Student > Ph. D. Student | 15 | 12% |
Student > Master | 14 | 11% |
Other | 12 | 10% |
Student > Bachelor | 10 | 8% |
Other | 27 | 22% |
Unknown | 21 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 57 | 46% |
Agricultural and Biological Sciences | 14 | 11% |
Nursing and Health Professions | 5 | 4% |
Biochemistry, Genetics and Molecular Biology | 4 | 3% |
Engineering | 4 | 3% |
Other | 9 | 7% |
Unknown | 30 | 24% |