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Attention Score in Context
Title |
High dose intermittent sorafenib shows improved efficacy over conventional continuous dose in renal cell carcinoma
|
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Published in |
Journal of Translational Medicine, December 2011
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DOI | 10.1186/1479-5876-9-220 |
Pubmed ID | |
Authors |
Xiaoen Wang, Liang Zhang, S Nahum Goldberg, Manoj Bhasin, Victoria Brown, David C Alsop, Sabina Signoretti, James W Mier, Michael B Atkins, Rupal S Bhatt |
Abstract |
Renal cell carcinoma (RCC) responds to agents that inhibit vascular endothelial growth factor (VEGF) pathway. Sorafenib, a multikinase inhibitor of VEGF receptor, is effective at producing tumor responses and delaying median progression free survival in patients with cytokine refractory RCC. However, resistance to therapy develops at a median of 5 months. In an effort to increase efficacy, we studied the effects of increased sorafenib dose and intermittent scheduling in a murine RCC xenograft model. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 32% |
Professor > Associate Professor | 3 | 16% |
Student > Ph. D. Student | 3 | 16% |
Student > Bachelor | 2 | 11% |
Professor | 1 | 5% |
Other | 1 | 5% |
Unknown | 3 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 4 | 21% |
Medicine and Dentistry | 4 | 21% |
Biochemistry, Genetics and Molecular Biology | 2 | 11% |
Engineering | 2 | 11% |
Physics and Astronomy | 1 | 5% |
Other | 2 | 11% |
Unknown | 4 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2021.
All research outputs
#3,758,979
of 22,660,862 outputs
Outputs from Journal of Translational Medicine
#601
of 3,951 outputs
Outputs of similar age
#31,873
of 243,043 outputs
Outputs of similar age from Journal of Translational Medicine
#9
of 59 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,951 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,043 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.