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Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study

Overview of attention for article published in Journal of Negative Results in BioMedicine, February 2016
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Title
Use of Diuretics is not associated with mortality in patients admitted to the emergency department: results from a cross-sectional study
Published in
Journal of Negative Results in BioMedicine, February 2016
DOI 10.1186/s12952-016-0044-1
Pubmed ID
Authors

Dominik G. Haider, Gregor Lindner, Michael Wolzt, Alexander Benedikt Leichtle, Georg-Martin Fiedler, Thomas C. Sauter, Valentin Fuhrmann, Aristomenis K. Exadaktylos

Abstract

Patients with diuretic therapy are at risk for drug-induced adverse reactions. It is unknown if presence of diuretic therapy at hospital emergency room admission is associated with mortality. In this cross sectional analysis, all emergency room patients 2010 and 2011 at the Inselspital Bern, Switzerland were included. A multivariable logistic regression model was performed to assess the association between pre-existing diuretic medication and 28 day mortality. Twenty-two thousand two hundred thirty-nine subjects were included in the analysis. A total of 8.5 %, 2.5 %, and 0.4 % of patients used one, two, or three or more diuretics. In univariate analysis spironolactone, torasemide and chlortalidone use were associated with 28 day mortality (all p < 0.05). In a multivariate cox regression model no association with mortality was detectable (p > 0.05). No difference existed between patients with or without diuretic therapy (P > 0.05). Age and creatinine were independent risk factors for mortaliy (both p < 0.05). Use of diuretics is not associated with mortality in an unselected cohort of patients presenting in an emergency room.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Other 2 20%
Student > Doctoral Student 1 10%
Student > Bachelor 1 10%
Student > Ph. D. Student 1 10%
Student > Master 1 10%
Other 2 20%
Unknown 2 20%
Readers by discipline Count As %
Medicine and Dentistry 5 50%
Nursing and Health Professions 1 10%
Pharmacology, Toxicology and Pharmaceutical Science 1 10%
Unknown 3 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 February 2016.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Journal of Negative Results in BioMedicine
#102
of 113 outputs
Outputs of similar age
#347,796
of 406,420 outputs
Outputs of similar age from Journal of Negative Results in BioMedicine
#6
of 6 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 113 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.