Title |
Geographical variation of Crohn's disease residual incidence in the Province of Quebec, Canada
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Published in |
International Journal of Health Geographics, May 2010
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DOI | 10.1186/1476-072x-9-22 |
Pubmed ID | |
Authors |
Pascal Michel, Laurie St-Onge, Anne-Marie Lowe, Michel Bigras-Poulin, Paul Brassard |
Abstract |
Crohn's disease (CD) is clinically expressed as a chronic affection of the gastrointestinal tract currently known to have a multifactorial etiology involving a complex pathophysiological host response modulated by genetic susceptibilities, demographic determinants and environmental factors. With more than 20 cases per 100,000 person-years, the province of Quebec, Canada is among regions of the world with highest reported occurrence of CD in relation to other places where comparable estimates are available. This ecological study was designed to provide a medium-scale spatial exploration of CD incidence after accounting for the influence of known population and regional determinants. Health records of consulting patients in southern Quebec were compiled from 1995 to 2000 and used to estimate age and sex standardized rates per health area (n = 156). Various statistical models taking into account the regional effect of Jewish ethnicity, aboriginal ancestry, material deprivation, prescription for oral contraceptives, reportable enteric infection incidence, smoking as well as latitude and longitude locations were fitted. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 3% |
Portugal | 1 | 2% |
Netherlands | 1 | 2% |
Unknown | 59 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 27% |
Student > Master | 14 | 22% |
Student > Ph. D. Student | 7 | 11% |
Student > Bachelor | 6 | 10% |
Professor > Associate Professor | 4 | 6% |
Other | 11 | 17% |
Unknown | 4 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 43% |
Agricultural and Biological Sciences | 10 | 16% |
Nursing and Health Professions | 4 | 6% |
Psychology | 3 | 5% |
Social Sciences | 3 | 5% |
Other | 9 | 14% |
Unknown | 7 | 11% |