Title |
Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study
|
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Published in |
Critical Care, October 2009
|
DOI | 10.1186/cc8145 |
Pubmed ID | |
Authors |
Russel J Roberts, Jeffrey F Barletta, Jeffrey J Fong, Greg Schumaker, Philip J Kuper, Stella Papadopoulos, Dinesh Yogaratnam, Elise Kendall, Renee Xamplas, Anthony T Gerlach, Paul M Szumita, Kevin E Anger, Paul A Arpino, Stacey A Voils, Philip Grgurich, Robin Ruthazer, John W Devlin |
Abstract |
While propofol is associated with an infusion syndrome (PRIS) that may cause death, the incidence of PRIS is unknown. Determining the incidence of PRIS and the frequency of PRIS-related clinical manifestations are key steps prior to the completion of any controlled studies investigating PRIS. This prospective, multicenter study sought to determine the incidence of PRIS and PRIS-related clinical manifestations in a large cohort of critically ill adults prescribed propofol. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 9 | 21% |
South Africa | 3 | 7% |
Spain | 2 | 5% |
United Kingdom | 2 | 5% |
Canada | 2 | 5% |
United Arab Emirates | 1 | 2% |
India | 1 | 2% |
Ecuador | 1 | 2% |
Malaysia | 1 | 2% |
Other | 6 | 14% |
Unknown | 15 | 35% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 27 | 63% |
Practitioners (doctors, other healthcare professionals) | 9 | 21% |
Scientists | 6 | 14% |
Science communicators (journalists, bloggers, editors) | 1 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 2% |
Spain | 2 | 1% |
United States | 2 | 1% |
France | 1 | <1% |
Belgium | 1 | <1% |
Brazil | 1 | <1% |
Japan | 1 | <1% |
Switzerland | 1 | <1% |
Unknown | 173 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 37 | 20% |
Researcher | 27 | 15% |
Student > Postgraduate | 19 | 10% |
Professor > Associate Professor | 16 | 9% |
Student > Master | 13 | 7% |
Other | 47 | 25% |
Unknown | 26 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 122 | 66% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 4% |
Agricultural and Biological Sciences | 4 | 2% |
Physics and Astronomy | 3 | 2% |
Neuroscience | 3 | 2% |
Other | 9 | 5% |
Unknown | 36 | 19% |