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Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response

Overview of attention for article published in Arthritis Research & Therapy, August 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

blogs
1 blog
patent
1 patent
f1000
1 research highlight platform

Citations

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101 Dimensions

Readers on

mendeley
81 Mendeley
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Title
Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response
Published in
Arthritis Research & Therapy, August 2009
DOI 10.1186/ar2798
Pubmed ID
Authors

Magda Nakou, Georgios Katsikas, Prodromos Sidiropoulos, George Bertsias, Eva Papadimitraki, Amalia Raptopoulou, Helen Koutala, Helen A Papadaki, Herakles Kritikos, Dimitrios T Boumpas

Abstract

Bone marrow (BM) is an immunologically privileged site where activated autoantibody-producing B cells may survive for prolonged periods. We investigated the effect of rituximab (anti-CD20 mAb) in peripheral blood (PB) and BM B-cell and T-cell populations in active rheumatoid arthritis (RA) patients.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Uzbekistan 1 1%
Italy 1 1%
Unknown 78 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Researcher 15 19%
Student > Master 6 7%
Student > Bachelor 5 6%
Other 5 6%
Other 16 20%
Unknown 18 22%
Readers by discipline Count As %
Medicine and Dentistry 31 38%
Agricultural and Biological Sciences 10 12%
Immunology and Microbiology 9 11%
Biochemistry, Genetics and Molecular Biology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 4 5%
Unknown 21 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2017.
All research outputs
#3,335,206
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#714
of 3,380 outputs
Outputs of similar age
#11,265
of 101,028 outputs
Outputs of similar age from Arthritis Research & Therapy
#5
of 24 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 101,028 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.