Title |
Substantial deletion overlap among divergent Arabidopsis genomes revealed by intersection of short reads and tiling arrays
|
---|---|
Published in |
Genome Biology, January 2010
|
DOI | 10.1186/gb-2010-11-1-r4 |
Pubmed ID | |
Authors |
Luca Santuari, Sylvain Pradervand, Amelia-Maria Amiguet-Vercher, Jerôme Thomas, Eavan Dorcey, Keith Harshman, Ioannis Xenarios, Thomas E Juenger, Christian S Hardtke |
Abstract |
Identification of small polymorphisms from next generation sequencing short read data is relatively easy, but detection of larger deletions is less straightforward. Here, we analyzed four divergent Arabidopsis accessions and found that intersection of absent short read coverage with weak tiling array hybridization signal reliably flags deletions. Interestingly, individual deletions were frequently observed in two or more of the accessions examined, suggesting that variation in gene content partly reflects a common history of deletion events. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 5% |
France | 1 | 2% |
Norway | 1 | 2% |
Germany | 1 | 2% |
Sweden | 1 | 2% |
Brazil | 1 | 2% |
China | 1 | 2% |
United Kingdom | 1 | 2% |
Unknown | 55 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 17 | 26% |
Student > Ph. D. Student | 17 | 26% |
Professor > Associate Professor | 10 | 15% |
Professor | 6 | 9% |
Student > Doctoral Student | 5 | 8% |
Other | 6 | 9% |
Unknown | 4 | 6% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 48 | 74% |
Computer Science | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Engineering | 2 | 3% |
Medicine and Dentistry | 2 | 3% |
Other | 1 | 2% |
Unknown | 7 | 11% |