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In vitromodel for the analysis of synovial fibroblast-mediated degradation of intact cartilage

Overview of attention for article published in Arthritis Research & Therapy, February 2009
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Citations

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Title
In vitromodel for the analysis of synovial fibroblast-mediated degradation of intact cartilage
Published in
Arthritis Research & Therapy, February 2009
DOI 10.1186/ar2618
Pubmed ID
Authors

David Pretzel, Dirk Pohlers, Sönke Weinert, Raimund W Kinne

Abstract

Activated synovial fibroblasts are thought to play a major role in the destruction of cartilage in chronic, inflammatory rheumatoid arthritis (RA). However, profound insight into the pathogenic mechanisms and the impact of synovial fibroblasts in the initial early stages of cartilage destruction is limited. Hence, the present study sought to establish a standardised in vitro model for early cartilage destruction with native, intact cartilage in order to analyse the matrix-degrading capacity of synovial fibroblasts and their influence on cartilage metabolism.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Denmark 1 1%
Unknown 85 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 33%
Student > Ph. D. Student 25 28%
Student > Bachelor 5 6%
Student > Master 5 6%
Professor > Associate Professor 4 5%
Other 13 15%
Unknown 7 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 22%
Biochemistry, Genetics and Molecular Biology 18 20%
Medicine and Dentistry 12 14%
Engineering 10 11%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Other 10 11%
Unknown 14 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2009.
All research outputs
#17,286,379
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#2,536
of 3,381 outputs
Outputs of similar age
#92,938
of 108,534 outputs
Outputs of similar age from Arthritis Research & Therapy
#24
of 30 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,534 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.