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Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene

Overview of attention for article published in BMC Developmental Biology, February 2008
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Title
Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene
Published in
BMC Developmental Biology, February 2008
DOI 10.1186/1471-213x-8-18
Pubmed ID
Authors

Emma Heath, Dalal Tahri, Elisabetta Andermarcher, Paul Schofield, Stewart Fleming, Catherine A Boulter

Abstract

Signals from the extracellular environment control many aspects of cell behaviour including proliferation, survival, differentiation, adhesion and migration. It is increasingly evident that these signals can be modulated by a group of matricellular proteins called the CCN family. CCN proteins have multiple domains through which they regulate the activities of a variety of signalling molecules including TGFbeta, BMPs and integrins, thereby influencing a wide range of processes in development and disease. Whilst the developmental roles of CCN1 and CCN2 have been elucidated, very little is known about the function of CCN3 (NOV). To investigate this, we have generated mice carrying a targeted mutation in the Nov gene (Novdel3) which reveal for the first time its diverse functions in embryos and adults.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 24%
Researcher 9 18%
Student > Master 8 16%
Professor > Associate Professor 5 10%
Student > Postgraduate 2 4%
Other 6 12%
Unknown 9 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 33%
Biochemistry, Genetics and Molecular Biology 9 18%
Medicine and Dentistry 7 14%
Veterinary Science and Veterinary Medicine 4 8%
Nursing and Health Professions 2 4%
Other 2 4%
Unknown 10 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2008.
All research outputs
#15,241,259
of 22,661,413 outputs
Outputs from BMC Developmental Biology
#258
of 369 outputs
Outputs of similar age
#68,054
of 79,895 outputs
Outputs of similar age from BMC Developmental Biology
#7
of 8 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 369 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 79,895 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one.