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Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis

Overview of attention for article published in Arthritis Research & Therapy, January 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

patent
2 patents
f1000
1 research highlight platform

Citations

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91 Dimensions

Readers on

mendeley
120 Mendeley
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Title
Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis
Published in
Arthritis Research & Therapy, January 2009
DOI 10.1186/ar2706
Pubmed ID
Authors

Wolfgang Hueber, Beren H Tomooka, Franak Batliwalla, Wentian Li, Paul A Monach, Robert J Tibshirani, Ronald F Van Vollenhoven, Jon Lampa, Kazuyoshi Saito, Yoshiya Tanaka, Mark C Genovese, Lars Klareskog, Peter K Gregersen, William H Robinson

Abstract

Anti-TNF therapies have revolutionized the treatment of rheumatoid arthritis (RA), a common systemic autoimmune disease involving destruction of the synovial joints. However, in the practice of rheumatology approximately one-third of patients demonstrate no clinical improvement in response to treatment with anti-TNF therapies, while another third demonstrate a partial response, and one-third an excellent and sustained response. Since no clinical or laboratory tests are available to predict response to anti-TNF therapies, great need exists for predictive biomarkers.

Mendeley readers

The data shown below were compiled from readership statistics for 120 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 3 3%
China 1 <1%
Colombia 1 <1%
Germany 1 <1%
Russia 1 <1%
United States 1 <1%
Philippines 1 <1%
Unknown 111 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 34 28%
Student > Ph. D. Student 22 18%
Student > Postgraduate 10 8%
Professor > Associate Professor 9 8%
Student > Bachelor 8 7%
Other 26 22%
Unknown 11 9%
Readers by discipline Count As %
Medicine and Dentistry 40 33%
Agricultural and Biological Sciences 38 32%
Biochemistry, Genetics and Molecular Biology 13 11%
Immunology and Microbiology 9 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 4 3%
Unknown 14 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2017.
All research outputs
#1,884,803
of 12,330,736 outputs
Outputs from Arthritis Research & Therapy
#452
of 1,947 outputs
Outputs of similar age
#34,783
of 238,816 outputs
Outputs of similar age from Arthritis Research & Therapy
#12
of 125 outputs
Altmetric has tracked 12,330,736 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,947 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 238,816 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.