↓ Skip to main content

Policing of gut microbiota by the adaptive immune system

Overview of attention for article published in BMC Medicine, February 2016
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

blogs
1 blog
twitter
12 X users

Citations

dimensions_citation
31 Dimensions

Readers on

mendeley
128 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Policing of gut microbiota by the adaptive immune system
Published in
BMC Medicine, February 2016
DOI 10.1186/s12916-016-0573-y
Pubmed ID
Authors

Laurent Dollé, Hao Q. Tran, Lucie Etienne-Mesmin, Benoit Chassaing

Abstract

The intestinal microbiota is a large and diverse microbial community that inhabits the intestine, containing about 100 trillion bacteria of 500-1000 distinct species that, collectively, provide benefits to the host. The human gut microbiota composition is determined by a myriad of factors, among them genetic and environmental, including diet and medication. The microbiota contributes to nutrient absorption and maturation of the immune system. As reciprocity, the host immune system plays a central role in shaping the composition and localization of the intestinal microbiota. Secretory immunoglobulins A (sIgAs), component of the adaptive immune system, are important player in the protection of epithelium, and are known to have an important impact on the regulation of microbiota composition. A recent study published in Immunity by Fransen and colleagues aimed to mechanistically decipher the interrelationship between sIgA and microbiota diversity/composition. This commentary will discuss these important new findings, as well as how future therapies can ultimately benefit from such discovery.

X Demographics

X Demographics

The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 <1%
Australia 1 <1%
Canada 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 123 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 16%
Student > Ph. D. Student 18 14%
Student > Bachelor 13 10%
Student > Master 12 9%
Student > Doctoral Student 8 6%
Other 26 20%
Unknown 31 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 18%
Biochemistry, Genetics and Molecular Biology 20 16%
Medicine and Dentistry 18 14%
Immunology and Microbiology 17 13%
Chemistry 3 2%
Other 14 11%
Unknown 33 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2016.
All research outputs
#2,249,354
of 22,846,662 outputs
Outputs from BMC Medicine
#1,464
of 3,435 outputs
Outputs of similar age
#42,961
of 400,467 outputs
Outputs of similar age from BMC Medicine
#21
of 56 outputs
Altmetric has tracked 22,846,662 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,435 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.6. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 400,467 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.