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Gut microbiome-host interactions in health and disease

Overview of attention for article published in Genome Medicine, March 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

news
5 news outlets
blogs
1 blog
policy
2 policy sources
twitter
7 X users
patent
5 patents
facebook
3 Facebook pages
reddit
1 Redditor

Citations

dimensions_citation
549 Dimensions

Readers on

mendeley
1144 Mendeley
citeulike
4 CiteULike
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Title
Gut microbiome-host interactions in health and disease
Published in
Genome Medicine, March 2011
DOI 10.1186/gm228
Pubmed ID
Authors

James M Kinross, Ara W Darzi, Jeremy K Nicholson

Abstract

The gut microbiome is the term given to describe the vast collection of symbiotic microorganisms in the human gastrointestinal system and their collective interacting genomes. Recent studies have suggested that the gut microbiome performs numerous important biochemical functions for the host, and disorders of the microbiome are associated with many and diverse human disease processes. Systems biology approaches based on next generation 'omics' technologies are now able to describe the gut microbiome at a detailed genetic and functional (transcriptomic, proteomic and metabolic) level, providing new insights into the importance of the gut microbiome in human health, and they are able to map microbiome variability between species, individuals and populations. This has established the importance of the gut microbiome in the disease pathogenesis for numerous systemic disease states, such as obesity and cardiovascular disease, and in intestinal conditions, such as inflammatory bowel disease. Thus, understanding microbiome activity is essential to the development of future personalized strategies of healthcare, as well as potentially providing new targets for drug development. Here, we review recent metagenomic and metabonomic approaches that have enabled advances in understanding gut microbiome activity in relation to human health, and gut microbial modulation for the treatment of disease. We also describe possible avenues of research in this rapidly growing field with respect to future personalized healthcare strategies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,144 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 24 2%
United Kingdom 8 <1%
Germany 4 <1%
Belgium 4 <1%
India 4 <1%
France 3 <1%
Spain 3 <1%
Canada 3 <1%
Brazil 2 <1%
Other 20 2%
Unknown 1069 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 214 19%
Researcher 179 16%
Student > Master 168 15%
Student > Bachelor 160 14%
Student > Doctoral Student 54 5%
Other 207 18%
Unknown 162 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 406 35%
Biochemistry, Genetics and Molecular Biology 155 14%
Medicine and Dentistry 143 13%
Immunology and Microbiology 64 6%
Environmental Science 26 2%
Other 158 14%
Unknown 192 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2023.
All research outputs
#712,534
of 25,374,647 outputs
Outputs from Genome Medicine
#137
of 1,585 outputs
Outputs of similar age
#2,407
of 120,011 outputs
Outputs of similar age from Genome Medicine
#1
of 8 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,585 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.8. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,011 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them