Title |
Detection of group A Streptococcus in tonsils from pediatric patients reveals high rate of asymptomatic streptococcal carriage
|
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Published in |
BMC Pediatrics, January 2012
|
DOI | 10.1186/1471-2431-12-3 |
Pubmed ID | |
Authors |
Amity L Roberts, Kristie L Connolly, Daniel J Kirse, Adele K Evans, Katherine A Poehling, Timothy R Peters, Sean D Reid |
Abstract |
Group A Streptococcus (GAS) causes acute tonsillopharyngitis in children, and approximately 20% of this population are chronic carriers of GAS. Antibacterial therapy has previously been shown to be insufficient at clearing GAS carriage. Bacterial biofilms are a surface-attached bacterial community that is encased in a matrix of extracellular polymeric substances. Biofilms have been shown to provide a protective niche against the immune response and antibiotic treatments, and are often associated with recurrent or chronic bacterial infections. The objective of this study was to test the hypothesis that GAS is present within tonsil tissue at the time of tonsillectomy. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 2% |
Tanzania, United Republic of | 1 | <1% |
Unknown | 117 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 22 | 18% |
Student > Ph. D. Student | 21 | 18% |
Student > Master | 11 | 9% |
Researcher | 11 | 9% |
Student > Postgraduate | 9 | 8% |
Other | 21 | 18% |
Unknown | 25 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 31 | 26% |
Immunology and Microbiology | 16 | 13% |
Agricultural and Biological Sciences | 16 | 13% |
Biochemistry, Genetics and Molecular Biology | 14 | 12% |
Unspecified | 3 | 3% |
Other | 12 | 10% |
Unknown | 28 | 23% |