Clara Natoli, Senior Author – “A multicenter study of body mass index (#BMI) in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable” @PAscierto @istitutotumori @univUda https://t.co/JHhLqPSoGp https:
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Although there are conflicting data, some studies, such as this one: https://t.co/tWQmfxLKSO suggest that patients with obesity suffer more IrAEs, but respond better to ICBs. Question is, how can we uncouple efficacy and toxicity... #immunotherapy
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It's not male (and melanoma) only; retrospective studies show both sexes and across cancers overweight is a predictive marker for response to checkpoint blockade; - https://t.co/uYgBNj5eny @sitcancer - https://t.co/qDlkaMl70d @PLOSONE - https://t.co/UfaD
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#JITC Research: A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable https://t.co/WTVcQ9PBwy