You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Widespread RNA binding by chromatin-associated proteins
|
|---|---|
| Published in |
Genome Biology, February 2016
|
| DOI | 10.1186/s13059-016-0878-3 |
| Pubmed ID | |
| Authors |
David G Hendrickson, David R. Kelley, Danielle Tenen, Bradley Bernstein, John L. Rinn |
| Abstract |
Recent evidence suggests that RNA interaction can regulate the activity and localization of chromatin-associated proteins. However, it is unknown if these observations are specialized instances for a few key RNAs and chromatin factors in specific contexts, or a general mechanism underlying the establishment of chromatin state and regulation of gene expression. Here, we perform formaldehyde RNA immunoprecipitation (fRIP-Seq) to survey the RNA associated with a panel of 24 chromatin regulators and traditional RNA binding proteins. For each protein that reproducibly bound measurable quantities of bulk RNA (90 % of the panel), we detect enrichment for hundreds to thousands of both noncoding and mRNA transcripts. For each protein, we find that the enriched sets of RNAs share distinct biochemical, functional, and chromatin properties. Thus, these data provide evidence for widespread specific and relevant RNA association across diverse classes of chromatin-modifying complexes. |
X Demographics
The data shown below were collected from the profiles of 67 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 19% |
| United Kingdom | 7 | 10% |
| France | 5 | 7% |
| Australia | 3 | 4% |
| Spain | 3 | 4% |
| Switzerland | 2 | 3% |
| Canada | 2 | 3% |
| Germany | 1 | 1% |
| India | 1 | 1% |
| Other | 0 | 0% |
| Unknown | 30 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 34 | 51% |
| Scientists | 31 | 46% |
| Practitioners (doctors, other healthcare professionals) | 1 | 1% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 408 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | <1% |
| United States | 2 | <1% |
| Czechia | 2 | <1% |
| Brazil | 1 | <1% |
| Sweden | 1 | <1% |
| Finland | 1 | <1% |
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| France | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 392 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 130 | 32% |
| Researcher | 73 | 18% |
| Student > Master | 33 | 8% |
| Student > Bachelor | 21 | 5% |
| Student > Doctoral Student | 20 | 5% |
| Other | 61 | 15% |
| Unknown | 70 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 179 | 44% |
| Agricultural and Biological Sciences | 119 | 29% |
| Computer Science | 13 | 3% |
| Immunology and Microbiology | 6 | 1% |
| Neuroscience | 6 | 1% |
| Other | 16 | 4% |
| Unknown | 69 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 37. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2022.
All research outputs
#1,093,636
of 25,374,647 outputs
Outputs from Genome Biology
#794
of 4,467 outputs
Outputs of similar age
#18,289
of 311,617 outputs
Outputs of similar age from Genome Biology
#12
of 61 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,617 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.