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X Demographics
Mendeley readers
Attention Score in Context
| Title |
CCR9 in cancer: oncogenic role and therapeutic targeting
|
|---|---|
| Published in |
Journal of Hematology & Oncology, February 2016
|
| DOI | 10.1186/s13045-016-0236-7 |
| Pubmed ID | |
| Authors |
Zhenbo Tu, Ruijing Xiao, Jie Xiong, Kingsley M. Tembo, Xinzhou Deng, Meng Xiong, Pan Liu, Meng Wang, Qiuping Zhang |
| Abstract |
Cancer is currently one of the leading causes of death worldwide and is one of the most challenging major public health problems. The main challenges faced by clinicians in the management and treatment of cancer mainly arise from difficulties in early diagnosis and the emergence of tumor chemoresistance and metastasis. The structures of chemokine receptor 9 (CCR9) and its specific ligand chemokine ligand 25 (CCL25) have been elucidated, and, interestingly, a number of studies have demonstrated that CCR9 is a potential tumor biomarker in diagnosis and therapy, as it has been found to be highly expressed in a wide range of cancers. This expression pattern suggests that CCR9 may participate in many important biological activities involved in cancer progression. Researchers have shown that CCR9 that has been activated by its specific ligand CCL25 can interact with many signaling pathways, especially those involved in tumor chemoresistance and metastasis. This review, therefore, focuses on CCR9 induction activity and summarizes what is currently known regarding its role in cancers and its potential application in tumor-targeted therapy. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 75 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 19% |
| Researcher | 12 | 16% |
| Student > Bachelor | 11 | 15% |
| Student > Ph. D. Student | 8 | 11% |
| Student > Doctoral Student | 2 | 3% |
| Other | 9 | 12% |
| Unknown | 19 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 28% |
| Agricultural and Biological Sciences | 9 | 12% |
| Immunology and Microbiology | 7 | 9% |
| Medicine and Dentistry | 6 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Other | 8 | 11% |
| Unknown | 21 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 March 2023.
All research outputs
#4,289,393
of 23,505,669 outputs
Outputs from Journal of Hematology & Oncology
#332
of 1,216 outputs
Outputs of similar age
#63,770
of 298,916 outputs
Outputs of similar age from Journal of Hematology & Oncology
#3
of 27 outputs
Altmetric has tracked 23,505,669 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,216 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,916 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.