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MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7

Overview of attention for article published in Breast Cancer Research, January 2012
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Title
MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7
Published in
Breast Cancer Research, January 2012
DOI 10.1186/bcr3098
Pubmed ID
Authors

Seok-Jun Kim, Ji-Young Shin, Kang-Duck Lee, Young-Ki Bae, Ki Woong Sung, Seok Jin Nam, Kyung-Hee Chun

Abstract

C-C chemokine receptor type 7 (CCR7) plays an important role in chemotactic and metastatic responses in various cancers, including breast cancer. In the present study, the authors demonstrated that microRNA (miRNA) let-7a downregulates CCR7 expression and directly influences the migration and invasion of breast cancer cells.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
China 1 1%
Austria 1 1%
Unknown 70 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 22%
Student > Bachelor 13 18%
Researcher 12 16%
Student > Master 9 12%
Student > Doctoral Student 5 7%
Other 9 12%
Unknown 10 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 23%
Agricultural and Biological Sciences 17 23%
Medicine and Dentistry 11 15%
Immunology and Microbiology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 7 9%
Unknown 15 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2012.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,705
of 2,052 outputs
Outputs of similar age
#203,888
of 251,542 outputs
Outputs of similar age from Breast Cancer Research
#35
of 40 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,542 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.