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5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis

Overview of attention for article published in Cancer Cell International, January 2012
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Title
5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis
Published in
Cancer Cell International, January 2012
DOI 10.1186/1475-2867-12-1
Pubmed ID
Authors

Friedrich G Kapp, Anette Sommer, Thomas Kiefer, Gottfried Dölken, Bernard Haendler

Abstract

Non-small cell lung cancer (NSCLC) is one of the most frequent malignancies and has a high mortality rate due to late detection and lack of efficient treatments. Identifying novel drug targets for this indication may open the way for new treatment strategies. Comparison of gene expression profiles of NSCLC and normal adjacent tissue (NAT) allowed to determine that 5-alpha-reductase type I (SRD5A1) was up-regulated in NSCLC compared to NAT. This raised the question whether SRD5A1 was involved in sustained proliferation and survival of NSCLC.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
South Africa 1 5%
Unknown 17 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 26%
Student > Master 3 16%
Student > Ph. D. Student 3 16%
Student > Bachelor 2 11%
Student > Postgraduate 2 11%
Other 2 11%
Unknown 2 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 21%
Medicine and Dentistry 4 21%
Chemistry 2 11%
Mathematics 1 5%
Immunology and Microbiology 1 5%
Other 3 16%
Unknown 4 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2012.
All research outputs
#18,303,566
of 22,661,413 outputs
Outputs from Cancer Cell International
#1,057
of 1,770 outputs
Outputs of similar age
#196,218
of 245,904 outputs
Outputs of similar age from Cancer Cell International
#8
of 13 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,770 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,904 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.