Title |
Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting
|
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Published in |
BMC Infectious Diseases, January 2012
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DOI | 10.1186/1471-2334-12-10 |
Pubmed ID | |
Authors |
Novel N Chegou, Gillian F Black, Andre G Loxton, Kim Stanley, Paulin N Essone, Michel R Klein, Shreemanta K Parida, Stefan HE Kaufmann, T Mark Doherty, Annemieke H Friggen, Kees L Franken, Tom H Ottenhoff, Gerhard Walzl |
Abstract |
Confirming tuberculosis (TB) disease in suspects in resource limited settings is challenging and calls for the development of more suitable diagnostic tools. Different Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens may be differentially recognized in infected and diseased individuals and therefore useful as diagnostic tools for differentiating between M.tb infection states. In this study, we assessed the diagnostic potential of 118 different M.tb infection phase-dependent antigens in TB patients and household contacts (HHCs) in a high-burden setting. |
X Demographics
Geographical breakdown
Country | Count | As % |
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South Africa | 2 | 50% |
United States | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Scientists | 1 | 25% |
Unknown | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Ukraine | 1 | <1% |
Australia | 1 | <1% |
Egypt | 1 | <1% |
Unknown | 113 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 21 | 18% |
Student > Master | 21 | 18% |
Student > Ph. D. Student | 20 | 17% |
Student > Postgraduate | 13 | 11% |
Student > Doctoral Student | 7 | 6% |
Other | 17 | 15% |
Unknown | 17 | 15% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 29 | 25% |
Agricultural and Biological Sciences | 21 | 18% |
Biochemistry, Genetics and Molecular Biology | 13 | 11% |
Immunology and Microbiology | 12 | 10% |
Nursing and Health Professions | 5 | 4% |
Other | 9 | 8% |
Unknown | 27 | 23% |