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Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas

Overview of attention for article published in Diagnostic Pathology, January 2012
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1 tweeter

Citations

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44 Mendeley
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Title
Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas
Published in
Diagnostic Pathology, January 2012
DOI 10.1186/1746-1596-7-8
Pubmed ID
Authors

Éva Gömöri, József Pál, Bernadett Kovács, Tamás Dóczi

Abstract

Gliomas are the most common neoplasm of the brain. High-grade gliomas often resist treatment even with aggressive surgical resection and adjuvant radiation and chemotherapy. Despite the combined treatment, they frequently recur with the same or higher-grade histology. Genetic instability is commonly associated with inactivation of the normal DNA repair function and tumour suppressor genes as well as activation of oncogenes resulting from alterations of promoter hypermethylation, but the molecular mechanisms of the histological and clinical progression of gliomas are still poorly understood.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nepal 1 2%
Denmark 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 8 18%
Student > Ph. D. Student 7 16%
Student > Master 6 14%
Researcher 5 11%
Student > Bachelor 4 9%
Other 10 23%
Unknown 4 9%
Readers by discipline Count As %
Medicine and Dentistry 14 32%
Agricultural and Biological Sciences 9 20%
Biochemistry, Genetics and Molecular Biology 7 16%
Neuroscience 3 7%
Computer Science 2 5%
Other 4 9%
Unknown 5 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2012.
All research outputs
#9,954,262
of 12,434,464 outputs
Outputs from Diagnostic Pathology
#469
of 758 outputs
Outputs of similar age
#155,256
of 220,591 outputs
Outputs of similar age from Diagnostic Pathology
#10
of 12 outputs
Altmetric has tracked 12,434,464 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 758 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,591 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.