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Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias

Overview of attention for article published in BMC Genomics, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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3 X users
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3 patents

Citations

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63 Dimensions

Readers on

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67 Mendeley
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1 CiteULike
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Title
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias
Published in
BMC Genomics, January 2012
DOI 10.1186/1471-2164-13-34
Pubmed ID
Authors

John P Didion, Hyuna Yang, Keith Sheppard, Chen-Ping Fu, Leonard McMillan, Fernando Pardo-Manuel de Villena, Gary A Churchill

Abstract

High-density genotyping arrays that measure hybridization of genomic DNA fragments to allele-specific oligonucleotide probes are widely used to genotype single nucleotide polymorphisms (SNPs) in genetic studies, including human genome-wide association studies. Hybridization intensities are converted to genotype calls by clustering algorithms that assign each sample to a genotype class at each SNP. Data for SNP probes that do not conform to the expected pattern of clustering are often discarded, contributing to ascertainment bias and resulting in lost information - as much as 50% in a recent genome-wide association study in dogs.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
Australia 1 1%
Canada 1 1%
Unknown 62 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 24%
Researcher 15 22%
Student > Master 10 15%
Student > Bachelor 8 12%
Professor > Associate Professor 4 6%
Other 11 16%
Unknown 3 4%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 55%
Computer Science 7 10%
Biochemistry, Genetics and Molecular Biology 6 9%
Medicine and Dentistry 3 4%
Immunology and Microbiology 2 3%
Other 5 7%
Unknown 7 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2021.
All research outputs
#3,759,146
of 22,661,413 outputs
Outputs from BMC Genomics
#1,550
of 10,612 outputs
Outputs of similar age
#32,613
of 245,768 outputs
Outputs of similar age from BMC Genomics
#43
of 279 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,612 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 245,768 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 279 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.