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The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer

Overview of attention for article published in Nutrition & Metabolism, February 2007
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)

Mentioned by

news
3 news outlets
blogs
4 blogs
twitter
89 X users
patent
2 patents
facebook
8 Facebook pages
wikipedia
2 Wikipedia pages
googleplus
4 Google+ users
reddit
1 Redditor
video
9 YouTube creators

Citations

dimensions_citation
253 Dimensions

Readers on

mendeley
388 Mendeley
citeulike
4 CiteULike
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Title
The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer
Published in
Nutrition & Metabolism, February 2007
DOI 10.1186/1743-7075-4-5
Pubmed ID
Authors

Weihua Zhou, Purna Mukherjee, Michael A Kiebish, William T Markis, John G Mantis, Thomas N Seyfried

Abstract

Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to provide long-term management because they ineffectively target tumor cells while negatively impacting the health and vitality of normal brain cells. In contrast to brain tumor cells, which lack metabolic flexibility and are largely dependent on glucose for growth and survival, normal brain cells can metabolize both glucose and ketone bodies for energy. This study evaluated the efficacy of KetoCal, a new nutritionally balanced high fat/low carbohydrate ketogenic diet for children with epilepsy, on the growth and vascularity of a malignant mouse astrocytoma (CT-2A) and a human malignant glioma (U87-MG).

X Demographics

X Demographics

The data shown below were collected from the profiles of 89 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 388 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
Germany 1 <1%
Israel 1 <1%
Portugal 1 <1%
Canada 1 <1%
India 1 <1%
Spain 1 <1%
Mexico 1 <1%
Unknown 378 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 79 20%
Student > Bachelor 57 15%
Researcher 45 12%
Student > Ph. D. Student 35 9%
Other 31 8%
Other 67 17%
Unknown 74 19%
Readers by discipline Count As %
Medicine and Dentistry 103 27%
Agricultural and Biological Sciences 59 15%
Biochemistry, Genetics and Molecular Biology 38 10%
Nursing and Health Professions 36 9%
Neuroscience 12 3%
Other 59 15%
Unknown 81 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 127. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2024.
All research outputs
#333,058
of 25,611,630 outputs
Outputs from Nutrition & Metabolism
#58
of 1,020 outputs
Outputs of similar age
#490
of 91,929 outputs
Outputs of similar age from Nutrition & Metabolism
#2
of 4 outputs
Altmetric has tracked 25,611,630 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,020 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 91,929 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.