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Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

Overview of attention for article published in BMC Cancer, January 2012
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  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

Mentioned by

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2 tweeters

Citations

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155 Dimensions

Readers on

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163 Mendeley
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Title
Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors
Published in
BMC Cancer, January 2012
DOI 10.1186/1471-2407-12-35
Pubmed ID
Authors

Anne-Katrine Bonde, Verena Tischler, Sushil Kumar, Alex Soltermann, Reto A Schwendener

Abstract

Several stromal cell subtypes including macrophages contribute to tumor progression by inducing epithelial-mesenchymal transition (EMT) at the invasive front, a mechanism also linked to metastasis. Tumor associated macrophages (TAM) reside mainly at the invasive front but they also infiltrate tumors and in this process they mainly assume a tumor promoting phenotype. In this study, we asked if TAMs also regulate EMT intratumorally. We found that TAMs through TGF-β signaling and activation of the β-catenin pathway can induce EMT in intratumoral cancer cells.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
Mexico 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 157 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 29%
Researcher 31 19%
Student > Master 19 12%
Student > Bachelor 13 8%
Student > Postgraduate 10 6%
Other 26 16%
Unknown 17 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 52 32%
Medicine and Dentistry 33 20%
Biochemistry, Genetics and Molecular Biology 28 17%
Engineering 9 6%
Immunology and Microbiology 9 6%
Other 13 8%
Unknown 19 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 January 2012.
All research outputs
#2,497,595
of 4,695,196 outputs
Outputs from BMC Cancer
#1,107
of 2,598 outputs
Outputs of similar age
#103,026
of 236,114 outputs
Outputs of similar age from BMC Cancer
#22
of 68 outputs
Altmetric has tracked 4,695,196 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,598 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,114 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.