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The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)

Overview of attention for article published in Arthritis Research & Therapy, November 2000
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1 patent

Citations

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47 Mendeley
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Title
The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)
Published in
Arthritis Research & Therapy, November 2000
DOI 10.1186/ar141
Pubmed ID
Authors

Maarten C Kraan, Dhavalkumar D Patel, Jasper J Haringman, Malcolm D Smith, Helen Weedon, Michael J Ahern, Ferdinand C Breedveld, Paul P Tak

Abstract

Paired synovial tissue samples were obtained from both clinically uninvolved (CU) and clinically involved (CI) knee joints of eight rheumatoid arthritis (RA) patients. In addition, biopsies were taken from five control subjects. We observed the expression of the chemokines CXCL8, CXCL9, CXCL10, CCL2 and CCL4 in CI and CU joints of RA patients. In particular, CXCL8 protein levels were specifically increased in CI joints compared with CU joints, which was confirmed by immunohistochemistry and in situ hybridization.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 1 2%
Czechia 1 2%
Canada 1 2%
Unknown 44 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 21%
Researcher 9 19%
Student > Bachelor 5 11%
Student > Master 4 9%
Other 4 9%
Other 10 21%
Unknown 5 11%
Readers by discipline Count As %
Medicine and Dentistry 11 23%
Agricultural and Biological Sciences 9 19%
Immunology and Microbiology 5 11%
Biochemistry, Genetics and Molecular Biology 5 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 13%
Unknown 9 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2003.
All research outputs
#8,533,995
of 25,371,288 outputs
Outputs from Arthritis Research & Therapy
#1,710
of 3,380 outputs
Outputs of similar age
#13,901
of 41,320 outputs
Outputs of similar age from Arthritis Research & Therapy
#3
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,380 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 41,320 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.