↓ Skip to main content

Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis

Overview of attention for article published in BMC Neuroscience, January 2012
Altmetric Badge

Mentioned by

twitter
1 X user

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
81 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Gender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis
Published in
BMC Neuroscience, January 2012
DOI 10.1186/1471-2202-13-12
Pubmed ID
Authors

Alessandro Massella, Giulia D'Intino, Mercedes Fernández, Sandra Sivilia, Luca Lorenzini, Silvia Giatti, Roberto C Melcangi, Laura Calzà, Luciana Giardino

Abstract

Multiple sclerosis (MS) varies considerably in its incidence and progression in females and males. In spite of clinical evidence, relatively few studies have explored molecular mechanisms possibly involved in gender-related differences. The present study describes possible cellular- and molecular-involved markers which are differentially regulated in male and female rats and result in gender-dependent EAE evolution and progression. Attention was focused on markers of myelination (MBP and PDGFαR) and neuronal distress and/or damage (GABA synthesis enzymes, GAD65 and GAD67, NGF, BDNF and related receptors), in two CNS areas, i.e. spinal cord and cerebellum, which are respectively severely and mildly affected by inflammation and demyelination. Tissues were sampled during acute, relapse/remission and chronic phases and results were analysed by two-way ANOVA.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
Ireland 1 1%
Italy 1 1%
United Kingdom 1 1%
United States 1 1%
Unknown 76 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 26%
Student > Ph. D. Student 17 21%
Student > Master 10 12%
Student > Doctoral Student 8 10%
Student > Postgraduate 4 5%
Other 10 12%
Unknown 11 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 26%
Neuroscience 15 19%
Medicine and Dentistry 9 11%
Biochemistry, Genetics and Molecular Biology 7 9%
Veterinary Science and Veterinary Medicine 4 5%
Other 7 9%
Unknown 18 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2012.
All research outputs
#18,304,230
of 22,662,201 outputs
Outputs from BMC Neuroscience
#878
of 1,240 outputs
Outputs of similar age
#196,423
of 246,185 outputs
Outputs of similar age from BMC Neuroscience
#17
of 22 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,185 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.