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TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation

Overview of attention for article published in Journal of Neuroinflammation, January 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)

Mentioned by

blogs
1 blog
twitter
7 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
221 Dimensions

Readers on

mendeley
178 Mendeley
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Title
TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation
Published in
Journal of Neuroinflammation, January 2012
DOI 10.1186/1742-2094-9-23
Pubmed ID
Authors

Karim Belarbi, Timothy Jopson, David Tweedie, Carla Arellano, Weiming Luo, Nigel H Greig, Susanna Rosi

Abstract

Chronic neuroinflammation is a hallmark of several neurological disorders associated with cognitive loss. Activated microglia and secreted factors such as tumor necrosis factor (TNF)-α are key mediators of neuroinflammation and may contribute to neuronal dysfunction. Our study was aimed to evaluate the therapeutic potential of a novel analog of thalidomide, 3,6'-dithiothalidomide (DT), an agent with anti-TNF-α activity, in a model of chronic neuroinflammation.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Luxembourg 2 1%
Australia 1 <1%
United Kingdom 1 <1%
Czechia 1 <1%
United States 1 <1%
Russia 1 <1%
Unknown 171 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 22%
Researcher 25 14%
Student > Bachelor 25 14%
Student > Master 24 13%
Professor > Associate Professor 10 6%
Other 30 17%
Unknown 25 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 47 26%
Medicine and Dentistry 33 19%
Neuroscience 25 14%
Psychology 8 4%
Biochemistry, Genetics and Molecular Biology 7 4%
Other 22 12%
Unknown 36 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2022.
All research outputs
#1,905,990
of 22,005,197 outputs
Outputs from Journal of Neuroinflammation
#228
of 2,539 outputs
Outputs of similar age
#17,017
of 251,040 outputs
Outputs of similar age from Journal of Neuroinflammation
#1
of 2 outputs
Altmetric has tracked 22,005,197 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,539 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,040 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them