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Cytoadherence and virulence - the case of Plasmodium knowlesi malaria

Overview of attention for article published in Malaria Journal, February 2012
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Mentioned by

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2 X users

Citations

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43 Dimensions

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94 Mendeley
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3 CiteULike
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Title
Cytoadherence and virulence - the case of Plasmodium knowlesi malaria
Published in
Malaria Journal, February 2012
DOI 10.1186/1475-2875-11-33
Pubmed ID
Authors

Farrah A Fatih, Angela Siner, Atique Ahmed, Lu Chan Woon, Alister G Craig, Balbir Singh, Sanjeev Krishna, Janet Cox-Singh

Abstract

Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria. Cytoadherence is mediated by specific binding of variant parasite antigens, expressed on the surface of infected erythrocytes, to endothelial receptors including, ICAM-1, VCAM and CD36. In fatal cases of severe falciparum malaria with coma, blood vessels in the brain are characteristically congested with infected erythrocytes. Brain sections from a fatal case of knowlesi malaria, but without coma, were similarly congested with infected erythrocytes. The objective of this study was to determine the binding phenotype of Plasmodium knowlesi infected human erythrocytes to recombinant human ICAM-1, VCAM and CD36.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Germany 1 1%
Kenya 1 1%
Indonesia 1 1%
Belgium 1 1%
United States 1 1%
Unknown 87 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 16%
Researcher 15 16%
Student > Bachelor 11 12%
Student > Master 10 11%
Student > Doctoral Student 5 5%
Other 17 18%
Unknown 21 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 32%
Medicine and Dentistry 18 19%
Biochemistry, Genetics and Molecular Biology 13 14%
Immunology and Microbiology 5 5%
Computer Science 2 2%
Other 3 3%
Unknown 23 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2012.
All research outputs
#13,359,802
of 22,662,201 outputs
Outputs from Malaria Journal
#3,496
of 5,538 outputs
Outputs of similar age
#146,395
of 247,565 outputs
Outputs of similar age from Malaria Journal
#45
of 64 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,538 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,565 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.