↓ Skip to main content

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria

Overview of attention for article published in Malaria Journal, February 2012
Altmetric Badge

About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 tweeters

Citations

dimensions_citation
42 Dimensions

Readers on

mendeley
90 Mendeley
citeulike
3 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Cytoadherence and virulence - the case of Plasmodium knowlesi malaria
Published in
Malaria Journal, February 2012
DOI 10.1186/1475-2875-11-33
Pubmed ID
Authors

Farrah A Fatih, Angela Siner, Atique Ahmed, Lu Chan Woon, Alister G Craig, Balbir Singh, Sanjeev Krishna, Janet Cox-Singh

Abstract

Cytoadherence of infected red blood cells to brain endothelium is causally implicated in malarial coma, one of the severe manifestations of falciparum malaria. Cytoadherence is mediated by specific binding of variant parasite antigens, expressed on the surface of infected erythrocytes, to endothelial receptors including, ICAM-1, VCAM and CD36. In fatal cases of severe falciparum malaria with coma, blood vessels in the brain are characteristically congested with infected erythrocytes. Brain sections from a fatal case of knowlesi malaria, but without coma, were similarly congested with infected erythrocytes. The objective of this study was to determine the binding phenotype of Plasmodium knowlesi infected human erythrocytes to recombinant human ICAM-1, VCAM and CD36.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Germany 1 1%
Kenya 1 1%
Indonesia 1 1%
Belgium 1 1%
United States 1 1%
Unknown 83 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 16%
Researcher 14 16%
Student > Master 11 12%
Student > Bachelor 11 12%
Student > Doctoral Student 5 6%
Other 18 20%
Unknown 17 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 33%
Medicine and Dentistry 18 20%
Biochemistry, Genetics and Molecular Biology 13 14%
Immunology and Microbiology 5 6%
Computer Science 2 2%
Other 4 4%
Unknown 18 20%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 February 2012.
All research outputs
#6,787,295
of 12,524,647 outputs
Outputs from Malaria Journal
#2,132
of 3,658 outputs
Outputs of similar age
#90,967
of 217,313 outputs
Outputs of similar age from Malaria Journal
#125
of 233 outputs
Altmetric has tracked 12,524,647 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,658 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 217,313 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 233 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.