Title |
Secondary amenorrhea in a woman with spinocerebellar degeneration treated with thyrotropin-releasing hormone: a case report and in vitro analysis
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Published in |
Journal of Medical Case Reports, December 2011
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DOI | 10.1186/1752-1947-5-567 |
Pubmed ID | |
Authors |
Haruhiko Kanasaki, Aki Oride, Tselmeg Mijiddorj, Indri Purwana, Kohji Miyazaki |
Abstract |
While thyrotropin-releasing hormone is known to be a prolactin-release stimulating factor, thyrotropin-releasing hormone-tartrate and its derivative, taltirelin hydrate, are used for the treatment of spinocerebellar degeneration, a degenerative disease characterized mainly by motor ataxia. We report the case of a patient being treated with a thyrotropin-releasing hormone preparation for spinocerebellar degeneration who developed amenorrhea after a dose increase. Her hormonal background was analyzed and the effect of prolonged exposure to thyrotropin-releasing hormone on pituitary prolactin-producing cells was examined in vitro. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 11 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 1 | 9% |
Student > Bachelor | 1 | 9% |
Student > Ph. D. Student | 1 | 9% |
Student > Master | 1 | 9% |
Researcher | 1 | 9% |
Other | 1 | 9% |
Unknown | 5 | 45% |
Readers by discipline | Count | As % |
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Nursing and Health Professions | 2 | 18% |
Neuroscience | 2 | 18% |
Biochemistry, Genetics and Molecular Biology | 1 | 9% |
Medicine and Dentistry | 1 | 9% |
Unknown | 5 | 45% |