@JasonRCantor @Cell_Metabolism @hankadel @HeatherKPhD @DMSabatini Congrats!! In our analysis we have shown that the media has a profound effect both RNAi and CRISPR screens: https://t.co/xElcuMdPjL
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RT @LagzielShoval: CRISPR and RNAi gene silencing screens are also highly affected by the choice of culture media. E.g. Asparagine syntheta…
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CRISPR and RNAi gene silencing screens are also highly affected by the choice of culture media. E.g. Asparagine synthetase (ASNS) was found to be more essential in cell lines cultured in media that lacks asparagine. https://t.co/xElcuMdPjL
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@FrezzaLab @biorxivpreprint Our paper "Inferring cancer dependencies on metabolic genes from large-scale genetic screens" is very relevant to this topic as well. https://t.co/xElcuMdPjL