Title |
Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)
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Published in |
BMC Neurology, February 2012
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DOI | 10.1186/1471-2377-12-3 |
Pubmed ID | |
Authors |
Christopher M Reid, Elsdon Storey, Tien Y Wong, Robyn Woods, Andrew Tonkin, Jie Jin Wang, Anthony Kam, Andrew Janke, Rowan Essex, Walter P Abhayaratna, Marc M Budge |
Abstract |
This paper describes the rationale and design of the ENVIS-ion Study, which aims to determine whether low-dose aspirin reduces the development of white matter hyper-intense (WMH) lesions and silent brain infarction (SBI). Additional aims include determining whether a) changes in retinal vascular imaging (RVI) parameters parallel changes in brain magnetic resonance imaging (MRI); b) changes in RVI parameters are observed with aspirin therapy; c) baseline cognitive function correlates with MRI and RVI parameters; d) changes in cognitive function correlate with changes in brain MRI and RVI and e) whether factors such as age, gender or blood pressure influence the above associations. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | <1% |
Germany | 1 | <1% |
Singapore | 1 | <1% |
Unknown | 114 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 23 | 20% |
Researcher | 15 | 13% |
Student > Master | 14 | 12% |
Student > Doctoral Student | 10 | 9% |
Student > Bachelor | 7 | 6% |
Other | 13 | 11% |
Unknown | 35 | 30% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 24 | 21% |
Psychology | 14 | 12% |
Nursing and Health Professions | 12 | 10% |
Neuroscience | 7 | 6% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Other | 16 | 14% |
Unknown | 39 | 33% |