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Overview of attention for article published in Malaria Journal, January 2003
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Mentioned by

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2 tweeters

Citations

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267 Dimensions

Readers on

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34 Mendeley
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1 CiteULike
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1 Connotea
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Title
Published in
Malaria Journal, January 2003
DOI 10.1186/1475-2875-2-27
Pubmed ID
Authors

Thomas Lavstsen, Ali Salanti, Anja TR Jensen, David E Arnot, Thor G Theander

Abstract

The variant surface antigen family Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) is an important target for protective immunity and is implicated in the pathology of malaria through its ability to adhere to host endothelial receptors. The sequence diversity and organization of the 3D7 PfEMP1 repertoire was investigated on the basis of the complete genome sequence. Using two tree-building methods we analysed the coding and non-coding sequences of 3D7 var and rif genes as well as var genes of other parasite strains. var genes can be sub-grouped into three major groups (group A, B and C) and two intermediate groups B/A and B/C representing transitions between the three major groups. The best defined var group, group A, comprises telomeric genes transcribed towards the telomere encoding PfEMP1s with complex domain structures different from the 4-domain type dominant of groups B and C. Two sequences belonging to the var1 and var2 subfamilies formed independent groups. A rif subgroup transcribed towards the centromere was found neighbouring var genes of group A such that the rif and var 5' regions merged. This organization appeared to be unique for the group A var genes The grouping of var genes implies that var gene recombination preferentially occurs within var gene groups and it is speculated that the groups reflect a functional diversification evolved to cope with the varying conditions of transmission and host immune response met by the parasite.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Kenya 3 9%
Germany 1 3%
France 1 3%
Tanzania, United Republic of 1 3%
United Kingdom 1 3%
United States 1 3%
Unknown 26 76%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 40 118%
Researcher 34 100%
Student > Master 21 62%
Student > Bachelor 20 59%
Student > Doctoral Student 9 26%
Other 13 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 66 194%
Biochemistry, Genetics and Molecular Biology 36 106%
Immunology and Microbiology 13 38%
Medicine and Dentistry 7 21%
Computer Science 2 6%
Other 5 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 June 2022.
All research outputs
#13,380,222
of 21,464,861 outputs
Outputs from Malaria Journal
#3,799
of 5,354 outputs
Outputs of similar age
#142,602
of 278,971 outputs
Outputs of similar age from Malaria Journal
#1
of 1 outputs
Altmetric has tracked 21,464,861 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,354 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,971 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them