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Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy

Overview of attention for article published in BMC Neuroscience, January 2012
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Title
Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy
Published in
BMC Neuroscience, January 2012
DOI 10.1186/1471-2202-13-15
Pubmed ID
Authors

Yong Fang Zhu, James L Henry

Abstract

Causes of neuropathic pain following nerve injury remain unclear, limiting the development of mechanism-based therapeutic approaches. Animal models have provided some directions, but little is known about the specific sensory neurons that undergo changes in such a way as to induce and maintain activation of sensory pain pathways. Our previous studies implicated changes in the Aβ, normally non-nociceptive neurons in activating spinal nociceptive neurons in a cuff-induced animal model of neuropathic pain and the present study was directed specifically at determining any change in excitability of these neurons. Thus, the present study aimed at recording intracellularly from Aβ-fiber dorsal root ganglion (DRG) neurons and determining excitability of the peripheral receptive field, of the cell body and of the dorsal roots.

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Iran, Islamic Republic of 1 2%
Portugal 1 2%
Unknown 55 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 24%
Student > Ph. D. Student 13 22%
Student > Master 4 7%
Student > Doctoral Student 3 5%
Professor > Associate Professor 3 5%
Other 13 22%
Unknown 9 15%
Readers by discipline Count As %
Medicine and Dentistry 17 29%
Neuroscience 7 12%
Agricultural and Biological Sciences 7 12%
Nursing and Health Professions 5 8%
Biochemistry, Genetics and Molecular Biology 4 7%
Other 8 14%
Unknown 11 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2012.
All research outputs
#2,903,366
of 3,628,496 outputs
Outputs from BMC Neuroscience
#453
of 568 outputs
Outputs of similar age
#167,747
of 230,791 outputs
Outputs of similar age from BMC Neuroscience
#17
of 22 outputs
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So far Altmetric has tracked 568 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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