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Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state

Overview of attention for article published in Journal of Translational Medicine, March 2016
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1 tweeter

Citations

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52 Mendeley
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Title
Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state
Published in
Journal of Translational Medicine, March 2016
DOI 10.1186/s12967-016-0821-0
Pubmed ID
Authors

Dandan Guan, Lidan Zhao, Daiwen Chen, Bing Yu, Jie Yu

Abstract

Fibroblast growth factor (FGF) 15/19 and FGF21 are two atypical members of FGF19 subfamily that function as hormones. Exogenous FGF15/19 and FGF21 have pharmacological effects, and endogenous FGF15/19 and FGF21 play vital roles in the maintenance of energy homeostasis. Recent reports have expanded the effects of FGF15/19 and FGF21 on carbohydrate and lipid metabolism. However, the regulations of FGF15/19 and FGF21 on metabolism are different. FGF15/19 is mainly secreted from the small intestine in response to feeding, and FGF21 is secreted from the liver in response to extended fasting and from the liver and adipose tissue in response to feeding. In this work, we reviewed the regulatory effects of FGF15/19 and FGF21 on metabolism in the fast and fed states. This information may provide some insight into the metabolic regulation of FGF15/19 and FGF21 in different physiological condition.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 21%
Student > Ph. D. Student 10 19%
Student > Bachelor 5 10%
Lecturer 3 6%
Other 3 6%
Other 8 15%
Unknown 12 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 27%
Medicine and Dentistry 8 15%
Agricultural and Biological Sciences 5 10%
Sports and Recreations 4 8%
Nursing and Health Professions 2 4%
Other 7 13%
Unknown 12 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2016.
All research outputs
#3,761,491
of 7,342,039 outputs
Outputs from Journal of Translational Medicine
#940
of 1,698 outputs
Outputs of similar age
#152,400
of 281,940 outputs
Outputs of similar age from Journal of Translational Medicine
#41
of 73 outputs
Altmetric has tracked 7,342,039 research outputs across all sources so far. This one is in the 28th percentile – i.e., 28% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,698 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,940 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.