Should we start looking at the DNA of #MycobacteriumTuberculosis directly from sputum/respiratory samples rather than culturing the bacterium and then looking at its genetic variability? This paper sheds a light; @BioMedCentral #tuberculosis #TB https://t
Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture. https://t.co/Rikj6GEZPp
To me the finding in this title seems very obvious? Or is that less obvious than i thought? "Whole genome sequencing Mycobacterium tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture" https://t.co/7GeLfecssq
what you'd expect certainly - but interesting to see the results. Though not entirely straightforward, it might help to parametrise models where individuals can be infected more than once.