Title |
Involvement of a periodontal pathogen, Porphyromonas gingivalis on the pathogenesis of non-alcoholic fatty liver disease
|
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Published in |
BMC Gastroenterology, February 2012
|
DOI | 10.1186/1471-230x-12-16 |
Pubmed ID | |
Authors |
Masato Yoneda, Shuhei Naka, Kazuhiko Nakano, Koichiro Wada, Hiroki Endo, Hironori Mawatari, Kento Imajo, Ryota Nomura, Kazuya Hokamura, Masafumi Ono, Shogo Murata, Iwai Tohnai, Yoshio Sumida, Toshihide Shima, Masae Kuboniwa, Kazuo Umemura, Yoshinori Kamisaki, Atsuo Amano, Takeshi Okanoue, Takashi Ooshima, Atsushi Nakajima |
Abstract |
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome that is closely associated with multiple factors such as obesity, hyperlipidemia and type 2 diabetes mellitus. However, other risk factors for the development of NAFLD are unclear. With the association between periodontal disease and the development of systemic diseases receiving increasing attention recently, we conducted this study to investigate the relationship between NAFLD and infection with Porphyromonas gingivalis (P. gingivalis), a major causative agent of periodontitis. |
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