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Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation

Overview of attention for article published in Arthritis Research & Therapy, November 2010
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Title
Eicosapentaenoic acid and docosahexaenoic acid reduce interleukin-1β-mediated cartilage degradation
Published in
Arthritis Research & Therapy, November 2010
DOI 10.1186/ar3183
Pubmed ID
Authors

Angus KT Wann, Jiten Mistry, Emma J Blain, Adina T Michael-Titus, Martin M Knight

Abstract

In inflammatory joint disease, such as osteoarthritis (OA), there is an increased level of proinflammatory cytokines, such as interleukin (IL)-1β. These cytokines stimulate the production of matrix metalloproteinases (MMPs), which leads to the degradation of the cartilage extracellular matrix and the loss of key structural components such as sulphated glycosaminoglycan (sGAG) and collagen II. The aim of this study was to examine the therapeutic potential of n-3 polyunsaturated fatty acids (PUFAs) in an in vitro model of cartilage inflammation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 3%
United States 1 2%
Unknown 59 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 18%
Researcher 10 16%
Student > Master 9 15%
Student > Ph. D. Student 7 11%
Student > Doctoral Student 6 10%
Other 10 16%
Unknown 9 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 23%
Medicine and Dentistry 13 21%
Biochemistry, Genetics and Molecular Biology 9 15%
Veterinary Science and Veterinary Medicine 5 8%
Nursing and Health Professions 3 5%
Other 8 13%
Unknown 10 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2013.
All research outputs
#15,517,312
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#2,262
of 3,381 outputs
Outputs of similar age
#86,360
of 110,627 outputs
Outputs of similar age from Arthritis Research & Therapy
#18
of 24 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,627 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.