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X Demographics
Mendeley readers
Attention Score in Context
| Title |
PDZ domains and their binding partners: structure, specificity, and modification
|
|---|---|
| Published in |
Cell Communication and Signaling, May 2010
|
| DOI | 10.1186/1478-811x-8-8 |
| Pubmed ID | |
| Authors |
Ho-Jin Lee, Jie J Zheng |
| Abstract |
PDZ domains are abundant protein interaction modules that often recognize short amino acid motifs at the C-termini of target proteins. They regulate multiple biological processes such as transport, ion channel signaling, and other signal transduction systems. This review discusses the structural characterization of PDZ domains and the use of recently emerging technologies such as proteomic arrays and peptide libraries to study the binding properties of PDZ-mediated interactions. Regulatory mechanisms responsible for PDZ-mediated interactions, such as phosphorylation in the PDZ ligands or PDZ domains, are also discussed. A better understanding of PDZ protein-protein interaction networks and regulatory mechanisms will improve our knowledge of many cellular and biological processes. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 830 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 1% |
| Germany | 3 | <1% |
| Australia | 2 | <1% |
| United Kingdom | 2 | <1% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Ireland | 1 | <1% |
| Hong Kong | 1 | <1% |
| Turkey | 1 | <1% |
| Other | 8 | <1% |
| Unknown | 801 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 233 | 28% |
| Student > Master | 114 | 14% |
| Researcher | 109 | 13% |
| Student > Bachelor | 105 | 13% |
| Student > Doctoral Student | 35 | 4% |
| Other | 98 | 12% |
| Unknown | 136 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 251 | 30% |
| Biochemistry, Genetics and Molecular Biology | 208 | 25% |
| Chemistry | 57 | 7% |
| Neuroscience | 44 | 5% |
| Medicine and Dentistry | 39 | 5% |
| Other | 86 | 10% |
| Unknown | 145 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2022.
All research outputs
#1,780,960
of 22,699,621 outputs
Outputs from Cell Communication and Signaling
#29
of 979 outputs
Outputs of similar age
#6,210
of 95,753 outputs
Outputs of similar age from Cell Communication and Signaling
#2
of 5 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 979 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.